- 1994- Establishment of Ponnaiyah Ramajayam College (PRC) Affiliated to Bharathidasan University 
- 2003- Ponnaiyah Ramajayam College approved as Research Institution by Bharathidasan University 
- 2004- NAAC ‘A’ Grade awarded to Ponnaiyah Ramajayam College. 
- 2004- Establishment of Ponnaiyah Ramajayam College of Education.  
- 2005- Ponnaiyah Ramajayam College recognized as a Research Institute by DSIR, Govt. of India.      
- 2008- Establishment of Ponnaiyah Ramajayam Institute of Science & Technology (PRIST), Institution Deemed to be University 
- 2008- Establishment of PRIST Deemed to be University Chennai ECR Campus. 
- 2008- Establishment of Centre for Distance Education in PRIST Deemed to be University.  
- 2009- Establishment of PRIST Deemed to be University campuses at Puducherry, Trichy and Kumbakonam.     
- 2012- Establishment of PRIST Deemed to be University, Madurai Campus. 
- 2013- AICTE Approval for PRIST Deemed to be University, Puducherry Campus. 
- 2014- Govt. of Tamil Nadu Recognition for PRIST Deemed to be University  
- 2015- NAAC Accreditation for PRIST Deemed to be University. 
- 2015- Bar Council of India (BCI) approval for School of Law in PRIST Deemed to be University, Madurai Campus 
- 2015- Council of Architecture (COA) approval for School of Architecture in PRIST Deemed to be University, Trichy Campus 
- 2016- NCTE Approval for offering BA., B.Ed., and B.Sc., B.Ed., courses in PRIST Deemed to be University 
- 2016- Council of Architecture (COA) approval for School of Architecture in PRIST Deemed to be University, Thanjavur Campus. 
- 2016- Pharmacy Council of India (PCI) approval for School of Pharmacy in PRIST Deemed to be University, Chennai ECR Campus. 
- 2016- School of Agriculture established to offer B.Sc. Agriculture & B.Tech (Agricultural Engineering) 
- 2017- Bar Council of India (BCI) approval for 3 year LLB course in School of Law, Madurai Campus 
- 2017- AICTE Approval for PRIST Deemed to be University Madurai Campus & Chennai ECR Campus 
- 2018- Establishment of PRIST Deemed to be University, Chennai CITY Campus. 
- 2018- AICTE Approval for PRIST Deemed to be University, Thanjavur Campus to offer Full Time & Part Time B.Tech. & M.Tech. Programmes 
- 2018- IIT Bombay Nodal Centre Approval for PRIST Deemed to be University 
- 2019- MHRD Extension of Approval for PRIST Deemed to be University 
- 2019- Institution Membership in MHRD Innovation Council (MIC) 
- 2019- Establishment of IPR Cell, Incubation Cell & Entrepreneurship Development Cell 
- 2019- Award of Double Star Ranking by MHRD, Institution’s Innovation Council